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Comparative study of GBP recruitment on two cytosol-dwelling pathogens, Francisella novicida and Shigella flexneri highlights differences in GBP repertoire and in GBP1 motif requirements

Stanimira Valeva , Manon Degabriel , Fanny Michal , Gabrielle Gay , John Rohde , et al.
Pathogens and Disease, 2023, 81, ⟨10.1093/femspd/ftad005⟩
Journal articles hal-04112340v1
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Faut-il rechercher un cancer après la découverte d’une granulomatose inexpliquée ?

P. Seve , Y. Jamilloux , M. Gerfaud-Valentin , T. El-Jammal , M. Pavic
La Revue de Médecine Interne, 2019, 40, pp.487 - 490. ⟨10.1016/j.revmed.2019.05.006⟩
Journal articles hal-03488140v1

Factors Associated with Ocular and Extraocular Recovery in 143 Patients with Sarcoid Uveitis

Francois-Henri Bienvenu , Theophile Tiffet , Delphine Maucort-Boulch , Mathieu Gerfaud-Valentin , Laurent Kodjikian , et al.
Journal of Clinical Medicine, 2020, 9, ⟨10.3390/jcm9123894⟩
Journal articles hal-03368089v1
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Fast diagnostic test for familial Mediterranean fever based on a kinase inhibitor

Flora Magnotti , Tiphaine Malsot , Sophie Georgin-Lavialle , Fatima Abbas , Amandine Martin , et al.
Annals of the Rheumatic Diseases, 2020, pp.annrheumdis-2020-218366. ⟨10.1136/annrheumdis-2020-218366⟩
Journal articles hal-02963374v1
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The Inflammasome Components NLRP3 and ASC Act in Concert with IRGM To Rearrange the Golgi Apparatus during Hepatitis C Virus Infection

Coralie Daussy , Sarah C Monard , Coralie Guy , Sara Muñoz-González , Maxime Chazal , et al.
Journal of Virology, 2021, 95 (3), pp.e00826-20. ⟨10.1128/JVI.00826-20⟩
Journal articles pasteur-03251892v1
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Irgm2 and Gate‐16 cooperatively dampen Gram‐negative bacteria‐induced caspase‐11 response

Elif Eren , Rémi Planès , Salimata Bagayoko , Pierre‐jean Bordignon , Karima Chaoui , et al.
EMBO Reports, 2020, 21 (11), ⟨10.15252/embr.202050829⟩
Journal articles hal-02997566v1
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Critical Role of a Sheath Phosphorylation Site On the Assembly and Function of an Atypical Type VI Secretion System

Jason Ziveri , Cerina Chhuon , Anne Jamet , Héloïse Rytter , Guénolé Prigent , et al.
Molecular and Cellular Proteomics, 2019, 18 (12), pp.2418 - 2432. ⟨10.1074/mcp.ra119.001532⟩
Journal articles hal-03012149v1

Pre-existing antibody-mediated adverse effects prevent the clinical development of a bacterial anti-inflammatory protein

Angelino Tromp , Yuxi Zhao , Ilse Jongerius , Erik Heezius , Pauline Abrial , et al.
Disease Models & Mechanisms, In press, pp.dmm.045534. ⟨10.1242/dmm.045534⟩
Journal articles hal-02865479v1
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Pyrin dephosphorylation is sufficient to trigger inflammasome activation in familial Mediterranean fever patients

Flora Magnotti , Lucie Lefeuvre , Sarah Benezech , Tiphaine Malsot , Louis Waeckel , et al.
EMBO Molecular Medicine, 2019, 11 (11), pp.e10547. ⟨10.15252/emmm.201910547⟩
Journal articles hal-02407259v1

A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells

Sacha Benaoudia , Amandine Martin , Marta Puig Gamez , Gabrielle Gay , Brice Lagrange , et al.
EMBO Reports, 2019, 20 (9), ⟨10.15252/embr.201948235⟩
Journal articles hal-02337614v1

Necrotizing Soft Tissue Infection Staphylococcus aureus but not S. pyogenes Isolates Display High Rates of Internalization and Cytotoxicity Toward Human Myoblasts

Jessica Baude , Sylvère Bastien , Yves Gillet , Pascal Leblanc , Andreas Itzek , et al.
Journal of Infectious Diseases, 2019, 220 (4), pp.710-719. ⟨10.1093/infdis/jiz167⟩
Journal articles hal-02323758v1

Pathophysiology, subtypes, and treatments of adult-onset Still's disease: An update

M. Gerfaud-Valentin , P. Sève , A. Hot , C. Broussolle , Yvan Jamilloux
La Revue de Médecine Interne, 2015, 36 (5), pp.319-327. ⟨10.1016/j.revmed.2014.10.365⟩
Journal articles hal-01953717v1

Les "guanylate binding proteins" : de nouveaux acteurs de l’immunité antibactérienne du cytosol des cellules hôtes

Pierre Wallet , Brice Lagrange , Thomas Henry
Médecine/Sciences, 2015, 31 (6-7), pp.600 - 603. ⟨10.1051/medsci/20153106009⟩
Journal articles hal-01927043v1

Francisella Inflammasomes: Integrated Responses to a Cytosolic Stealth Bacterium

Pierre Wallet , Brice Lagrange , Thomas Henry
Inflammasome Signaling and Bacterial Infections, 397, Springer, 2016, Current Topics in Microbiology and Immunology, 978-3-319-41170-5. ⟨10.1007/978-3-319-41171-2_12⟩
Book sections hal-01927023v1

Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida

Etienne Meunier , Pierre Wallet , Roland Dreier , Stéphanie Costanzo , Leonie Anton , et al.
Nature Immunology, 2015, 16 (5), pp.476 - 484. ⟨10.1038/ni.3119⟩
Journal articles hal-01924091v1

Familial Mediterranean fever mutations are hypermorphic mutations that specifically decrease the activation threshold of the Pyrin inflammasome

Yvan Jamilloux , Lucie Lefeuvre , Flora Magnotti , Amandine Martin , Sarah Benezech , et al.
Rheumatology, 2018, 57 (1), pp.100 - 111. ⟨10.1093/rheumatology/kex373⟩
Journal articles hal-01921022v1

Geoepidemiology and Immunologic Features of Autoinflammatory Diseases: a Comprehensive Review

Yvan Jamilloux , Alexandre Belot , Flora Magnotti , Sarah Benezech , Mathieu Gerfaud-Valentin , et al.
Clinical Reviews in Allergy and Immunology, 2018, 54 (3), pp.454 - 479. ⟨10.1007/s12016-017-8613-8⟩
Journal articles hal-01920971v1

A proximity-dependent biotinylation (BioID) approach flags the p62/sequestosome-1 protein as a caspase-1 substrate

Yvan Jamilloux , Brice Lagrange , Antonia Di Micco , Emilie Bourdonnay , Angélina Provost , et al.
Journal of Biological Chemistry, 2018, 293 (32), pp.12563-12575. ⟨10.1074/jbc.RA117.000435⟩
Journal articles hal-01917829v1

The pyrin inflammasome: from sensing RhoA GTPases-inhibiting toxins to triggering autoinflammatory syndromes

Yvan Jamilloux , Flora Magnotti , Alexandre Belot , Thomas Henry
Pathogens and Disease, 2018, 76 (3), ⟨10.1093/femspd/fty020⟩
Journal articles hal-01917828v1

Multiple Pseudomonas species secrete exolysin-like toxins and provoke Caspase-1-dependent macrophage death.

Pauline Basso , Pierre Wallet , Sylvie Elsen , Emmanuelle Soleilhac , Thomas Henry , et al.
Environmental Microbiology, 2017, 10, pp.4045-4064. ⟨10.1111/1462-2920.13841⟩
Journal articles hal-01911523v1

Kineret© IL-1ra blocks the IL-1/IL-8 inflammatory cascade during recombinant Panton Valentine Leukocidin-triggered pneumonia but not during S. aureus infection

Delphine Labrousse , Magali Perret , Davy Hayez , Sonia da Silva , Cédric Badiou , et al.
PLoS ONE, 2014, 9 (6), pp.e97546. ⟨10.1371/journal.pone.0097546⟩
Journal articles hal-01911490v1

LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation

José Carlos Santos , Mathias S. Dick , Brice Lagrange , Daniel Degrandi , Klaus Pfeffer , et al.
EMBO Journal, 2018, 37 (6), ⟨10.15252/embj.201798089⟩
Journal articles hal-01911461v1

The inflammasomes: platforms of innate immunity

Yvan Jamilloux , Thomas Henry
Médecine/Sciences, 2013, 29 (11), pp.975-984. ⟨10.1051/medsci/20132911013⟩
Journal articles hal-01911444v1

Inflammasomes in human diseases

Yvan Jamilloux , P. Sève , Thomas Henry
La Revue de Médecine Interne, 2014, 35 (11), pp.730-741. ⟨10.1016/j.revmed.2014.04.017⟩
Journal articles hal-01911443v1

Importance of host cell arginine uptake in Francisella phagosomal escape and ribosomal protein amounts

Elodie Ramond , Gael Gesbert , Ida Chiara Guerrera , Cerina Chhuon , Marion Dupuis , et al.
Molecular and Cellular Proteomics, 2015, 14 (4), pp.870-881. ⟨10.1074/mcp.M114.044552⟩
Journal articles hal-01911436v1

Inherited anomalies of innate immune receptors in pediatric-onset inflammatory diseases

Cécile Picard , Anne-Laure Mathieu , Uzma Hasan , Thomas Henry , Yvan Jamilloux , et al.
Autoimmunity Reviews, 2015, 14 (12), pp.1147-1153. ⟨10.1016/j.autrev.2015.08.002⟩
Journal articles hal-01911433v1

An In Vitro Co-culture Mouse Model Demonstrates Efficient Vaccine-Mediated Control of Francisella tularensis SCHU S4 and Identifies Nitric Oxide as a Predictor of Efficacy

Igor Golovliov , Helena Lindgren , Kjell Eneslätt , Wayne Conlan , Amandine Mosnier , et al.
Frontiers in Cellular and Infection Microbiology, 2016, 6, pp.152. ⟨10.3389/fcimb.2016.00152⟩
Journal articles hal-01911430v1

IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection

Pierre Wallet , Sacha Benaoudia , Amandine Mosnier , Brice Lagrange , Amandine Martin , et al.
PLoS Pathogens, 2017, 13 (10), pp.e1006630. ⟨10.1371/journal.ppat.1006630⟩
Journal articles hal-01911420v1

Human Monocyte-Derived Osteoclasts Are Targeted by Staphylococcal Pore-Forming Toxins and Superantigens

Sacha Flammier , Jean-Philippe Rasigade , Cédric Badiou , Thomas Henry , François Vandenesch , et al.
PLoS ONE, 2016, 11 (3), pp.e0150693. ⟨10.1371/journal.pone.0150693⟩
Journal articles hal-01911342v1

Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin

Angelino T. Tromp , Michiel van Gent , Pauline Abrial , Amandine Martin , Joris P. Jansen , et al.
Nature Microbiology, 2018, 3 (6), pp.708-717. ⟨10.1038/s41564-018-0159-x⟩
Journal articles hal-01911327v1