%0 Journal Article %T Prevalence and covariates of electrocardiographic left ventricular hypertrophy in the Hypertension in the Very Elderly Trial. %+ Centre for Epidemiological Studies and Clinical Trials %+ Centre for Cancer Genetic Epidemiology %+ Handicap, Activité, Vieillissement, Autonomie, Environnement (HAVAE) %+ Service de Médecine Gériatrique [CHU Limoges] %A Antikainen, Riitta L %A Beckett, Nigel %A Peters, Ruth %A Fagard, Robert %A Rajkumar, Chakravarthi %A Wang, Jiguang %A Stoyanovsky, Vassil %A Barrowdale, Daniel %A Bulpitt, Christopher J %A Dantoine, Thierry %A Hyvet Study, Group %< avec comité de lecture %@ 0263-6352 %J Journal of Hypertension %I Lippincott, Williams & Wilkins %V 31 %N 6 %P 1224-32 %8 2013-06 %D 2013 %R 10.1097/HJH.0b013e32836040a4 %M 23588194 %Z Life Sciences [q-bio]/Human health and pathologyJournal articles %X OBJECTIVE: To estimate the prevalence and covariates of electrocardiographic left ventricular hypertrophy (LVH) in the Hypertension in the Very Elderly Trial. METHODS: A total of 2993 hypertensive people aged at least 80 years with technically codable ECGs without pacing, bundle branch block, or ECG myocardial infarction were studied. LVH was assessed using Sokolow-Lyon (SL-LVH), Cornell voltage (CV-LVH), and Cornell product criterion (CP-LVH). RESULTS: The prevalence of LVH varied from 2.4 to 17.5% depending on sex, race, and ECG criterion. The highest prevalence of SL-LVH (12.0%) was in Chinese men and in white women for both CV-LVH (17.5%) and CP-LVH (12.9%). Increasing SBP was an independent covariate of the presence of LVH in Chinese women independently of the criterion used (β = 0.052-0.069, P < 0.001), of SL-LVH in Chinese men (β = 0.047 P = 0.006). In white women, CP-LVH was associated with increasing age (β = 0.055, P = 0.027) and SBP (β = 0.023, P = 0.040). Increasing BMI was associated inversely with SL-LVH; the association in white men only was not significant. In white men, a history of diabetes was directly and history of antihypertensive drug treatment inversely related to CV-LVH and CP-LVH. SL-ECG was associated inversely to serum uric acid concentration in Chinese women and to serum hemoglobin concentration in Chinese men. CONCLUSION: Prevalence and covariates of electrocardiographic LVH varied by sex, race, and ECG criterion. CP-LVH may prove to be the most useful measure of LVH in this study owing to its close relationship to SBP, at least in women, and independence from BMI. %G English %L hal-00842615 %U https://unilim.hal.science/hal-00842615 %~ UNILIM %~ HAVAE %~ GEIST %~ OMEGAHEALTH