%0 Journal Article %T The development of rediae of Fasciola hepatica in Radix natalensis subjected twice to bimiracidial exposures. %+ Neuroépidémiologie Tropicale et Comparée (NETEC) %+ Université de Limoges (UNILIM) %A Dar, Y. %A Vignoles, Philippe %A Dreyfuss, Gilles %A Rondelaud, Daniel %< avec comité de lecture %@ 0022-149X %J Journal of Helminthology %I Cambridge University Press (CUP) %P 1-5 %8 2010-09-08 %D 2010 %R 10.1017/S0022149X10000453 %M 20822573 %Z Life Sciences [q-bio]/Santé publique et épidémiologieJournal articles %X Experimental infections of Egyptian Radix natalensis with a French isolate of Fasciola hepatica (each snail was subjected twice to a bimiracidial exposure) were carried out to determine how many sporocysts grew in these snails and to study the developmental patterns of redial generations. Single-sporocyst infections were found in 69.3% (34/49) of infected snails, with equivalent numbers of normal and abnormal patterns. Snails with two- and three-sporocyst infections were 24.4% and 6.1%, respectively. In single- and two-sporocyst infections at days 42 and 56 post-exposure, the total redial burden was significantly higher in snails with a normal redial development. In two- and three-sporocyst infections, the overall maturity of rediae was delayed at days 42 and 56. The high frequency of abnormal patterns in R. natalensis (53.1% of all infected snails showed degeneration of a first mother redia) might be due to incomplete adaptation between the snail population and the parasite. The delayed redial maturity in two- and three-sporocyst infections can mainly be explained by the volume of the snail body, which would be insufficient to allow the simultaneous differentiation of most rediae over time. %G English %L hal-00934788 %U https://unilim.hal.science/hal-00934788 %~ UNILIM %~ CNRS %~ NET %~ SANTE_PUB_INSERM %~ GEIST %~ EPIMACT %~ OMEGAHEALTH