%0 Journal Article %T High Prevalence of Asymptomatic Neurocysticercosis in an Endemic Rural Community in Peru. %+ Neuroépidémiologie Tropicale (NET) %+ Universidad Peruana Cayetano Heredia (UPCH) %+ Georgia State University %+ Johns Hopkins University (JHU) %A Moyano, Luz Maria %A O’neal, Seth E. %A Ayvar, Viterbo %A Gonzalvez, Guillermo %A Gamboa, Ricardo %A Vilchez, Percy %A Rodriguez, Silvia %A Reistetter, Joe %A Tsang, Victor C W %A Gilman, Robert H %A Gonzalez, Armando E %A Garcia, Hector H %A Working Group In Peru, The Cysticercosis %< avec comité de lecture %@ 1935-2727 %J PLoS Neglected Tropical Diseases %I Public Library of Science %V 10 %N 12 %P e0005130 %8 2016-12-19 %D 2016 %M 27992429 %Z Life Sciences [q-bio]/Santé publique et épidémiologieJournal articles %X Neurocysticercosis is a common helminthic infection of the central nervous system and an important cause of adult-onset epilepsy in endemic countries. However, few studies have examined associations between neurologic symptoms, serology and radiographic findings on a community-level. %X We conducted a population-based study of resident's ≥2 years old in a highly endemic village in Peru (pop. 454). We applied a 14 -question neurologic screening tool and evaluated serum for antibodies against Taenia solium cysticercosis using enzyme-linked immunoelectrotransfer blot (LLGP-EITB). We invited all residents ≥18 years old to have non-contrast computerized tomography (CT) of the head. %X Of the 385 residents who provided serum samples, 142 (36.9%) were seropositive. Of the 256 residents who underwent CT scan, 48 (18.8%) had brain calcifications consistent with NCC; 8/48 (17.0%) reported a history of headache and/or seizures. Exposure to T. solium is very common in this endemic community where 1 out of 5 residents had brain calcifications. However, the vast majority of people with calcifications were asymptomatic. %X This study reports a high prevalence of NCC infection in an endemic community in Peru and confirms that a large proportion of apparently asymptomatic residents have brain calcifications that could provoke seizures in the future. %G English %L hal-01425082 %U https://unilim.hal.science/hal-01425082 %~ UNILIM %~ NET %~ SANTE_PUB_INSERM %~ GEIST %~ EPIMACT %~ OMEGAHEALTH %~ LABCIS