Life in an unsuspected antibiotics world: River biofilms - Université de Limoges Accéder directement au contenu
Article Dans Une Revue Water Research Année : 2023

Life in an unsuspected antibiotics world: River biofilms


Waterborne bacteria that naturally live in biofilms are continuously exposed to pharmaceutical residues, regularly released into the freshwater environment. At the source level, the discharge of antibiotics into rivers has already been repeatedly linked to the development of antimicrobial resistance. But what about biofilms away from the discharge point? Two rivers, with sites subject to dispersed contamination of medium intensity, were studied as typical representatives of high-and middle-income countries. The biofilms developed on rocks indigenous to rivers are perfectly representative of environmental exposure. Our results show that away from the hotspots, the amount of antibiotics in the biofilms studied favours the maintenance and enrichment of existing resistant strains as well as the selection of new resistant mutants, and these favourable conditions remain over a period of time. Thus, in this type of river, the environmental risk of selection pressure is not only present downstream of urbanised areas but is also possible upstream and far downstream of wastewater treatment plant discharges. Despite this, correlation analysis found no strong positive correlation between antibiotic concentrations and the abundance of measured integrons and their corresponding resistance genes. Nevertheless, this work highlights the need to consider the risks of antibiotics beyond hotspots as well.
Fichier principal
Vignette du fichier
Manuscript Matviichuk et al 2022_WR_HAL.pdf (928.67 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-04032840 , version 1 (16-03-2023)



Olha Matviichuk, Leslie Mondamert, Claude Geffroy, Christophe Dagot, Jérôme Labanowski. Life in an unsuspected antibiotics world: River biofilms. Water Research, 2023, 231, pp.119611. ⟨10.1016/j.watres.2023.119611⟩. ⟨hal-04032840⟩
7 Consultations
18 Téléchargements



Gmail Facebook Twitter LinkedIn More