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Sonic hedgehog activation is implicated in diosgenin-induced megakaryocytic differentiation of human erythroleukemia cells

Lamia Ghezali , Bertrand Liagre , Youness Limami , Jean-Louis Beneytout , David Yannick Leger
PLoS ONE, 2014, 9 (4), pp.e95016. ⟨10.1371/journal.pone.0095016⟩
Article dans une revue hal-01058423v1
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Dimethyl Sulfoxide: A Bio-Friendly or Bio-Hazard Chemical? The Effect of DMSO in Human Fibroblast-like Synoviocytes

Manuel Gallardo-Villagr , Lucie Paulus , David Yannick Leger , Bruno Therrien , Bertrand Liagre
Molecules, 2022, 27 (14), pp.4472. ⟨10.3390/molecules27144472⟩
Article dans une revue hal-03722376v1

Novel methylsulfonyl chalcones as potential antiproliferative drugs for human prostate cancer: Involvement of the intrinsic pathway of apoptosis

Bassel Ismail , Lamia Ghezali , Rockhaya Gueye , Youness Limami , Christelle Pouget , et al.
International Journal of Oncology, 2013, 43 (4), pp.1160-1168. ⟨10.3892/ijo.2013.2024⟩
Article dans une revue hal-00937783v1
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Porphyrin-xylan-coated silica nanoparticles for anticancer photodynamic therapy

Soukaina Bouramtane , Ludovic Bretin , Aline Pinon , David Leger , Bertrand Liagre , et al.
Carbohydrate Polymers, 2019, 213, pp.168-175. ⟨10.1016/j.carbpol.2019.02.070⟩
Article dans une revue hal-02490804v1
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Enhanced cytotoxicity of gold porphyrin complexes after inclusion in cyclodextrin scaffolds adsorbed on polyethyleneimine-coated gold nanoparticles

Robert Granet , René Faure , Gautier Mark-Arthur Ndong Ntoutoume , Jean Pierre Mbakidi , David Yann Leger , et al.
Bioorganic and Medicinal Chemistry Letters, 2019, 29 (9), pp.1065-1068. ⟨10.1016/j.bmcl.2019.03.003⟩
Article dans une revue hal-02922086v1

Honey-induced macrophage stimulation: AP-1 and NF-κB activation and cytokine production are unrelated to LPS content of honey

Anais Raynaud , Lamia Guezali , Vincent Gloaguen , Bertrand Liagre , Fabien Quero , et al.
International Immunopharmacology, 2013, 17 (3), pp.874-879. ⟨10.1016/j.intimp.2013.09.014⟩
Article dans une revue hal-00935716v1
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Novel Set of Diarylmethanes to Target Colorectal Cancer: Synthesis, In Vitro and In Silico Studies

Ameni Hadj Mohamed , Aline Pinon , Nathalie Lagarde , Elizabeth Goya Jorge , Hadley Mouhsine , et al.
Biomolecules, 2023, 13 (1), pp.54. ⟨10.3390/biom13010054⟩
Article dans une revue hal-03929804v1

Growth Inhibitory and Pro-Apoptotic Effects of Ornamental Pomegranate Extracts in Du145 Human Prostate Cancer Cells

Zahra Amri , Wafa Kharroubi , Chloë Fidanzi-Dugas , David Yannick Leger , Mohamed Hammami , et al.
Nutrition and Cancer, 2020, 72 (6), pp.932-938. ⟨10.1080/01635581.2019.1660385⟩
Article dans une revue hal-02922065v1

Development of curcumin-cyclodextrin/cellulose nanocrystals complexes: New anticancer drug delivery systems

Gautier Mark Arthur Ndong Ntoutoume , Robert Granet , Jean-Pierre Mbakidi , Frédérique Brégier , David Yannick Leger , et al.
Bioorganic and Medicinal Chemistry Letters, 2016, 26, pp.941-945. ⟨10.1016/j.bmcl.2015.12.060⟩
Article dans une revue hal-01257118v1

Analysis of relationship between cell cycle stage and apoptosis induction in K562 cells by sedimentation field-flow fractionation.

Julian Bertrand , Bertrand Liagre , Gaëlle Bégaud-Grimaud , Marie-Odile Jauberteau-Marchan , Jean-Louis Beneytout , et al.
Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2009, 877 (11-12), pp.1155-1161. ⟨10.1016/j.jchromb.2009.02.064⟩
Article dans une revue istex hal-00595229v1

Diosgenin induces cell cycle arrest and apoptosis in HEL cells with increase in intracellular calcium level, activation of cPLA2 and COX-2 overexpression.

David Leger , Bertrand Liagre , Cécile Corbière , Jeanne Cook-Moreau , Jean-Louis Beneytout
International Journal of Oncology, 2004, 25 (3), pp.555-62
Article dans une revue hal-02340682v1

The anti-apoptotic property of NS-398 at high dose can be mediated in part through NF-kappaB activation, hsp70 induction and a decrease in caspase-3 activity in human osteosarcoma cells.

Sandra Moalic-Juge , Bertrand Liagre , Raphael E Duval , Cécile Corbière , Arnaud Bianchi , et al.
International Journal of Oncology, 2002, 20 (6), pp.1255-62. ⟨10.3892/ijo.20.6.1255⟩
Article dans une revue hal-02340688v1

Diarylmethanes as potential anti colorectal cancer agents: Synthesis, In vitro and in silico studies

Maité Sylla-Iyarreta , Ameni Hadj Mohamed , Aline Pinon , Nathalie Lagarde , Bertrand Liagre
30ème Young Research Fellows Meeting, SCT, Apr 2023, Paris, France
Communication dans un congrès hal-04058639v1

Polyphenol-Based Nanoparticles: A Promising Frontier for Enhanced Colorectal Cancer Treatment

Hicham Wahnou , Bertrand Liagre , Vincent Sol , Hicham El Attar , Rukset Attar , et al.
Cancers, 2023, 15 (15), pp.3826. ⟨10.3390/cancers15153826⟩
Article dans une revue hal-04196379v1

Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression.

Bertrand Liagre , Pascale Vergne-Salle , Cécile Corbière , Jean Charissoux , Jean Beneytout
Arthritis Research and Therapy, 2004, 6 (4), pp.R373. ⟨10.1186/ar1199⟩
Article dans une revue hal-02340686v1

Antitumoral activity of Caralluma europaea on colorectal and prostate cancer cell lines

Inass Samiry , Aline Pinon , Youness Limami , Samira Rais , Younes Zaid , et al.
Journal of Toxicology and Environmental Health, Part A: Current Issues, 2023, 86 (7), pp.230-240. ⟨10.1080/15287394.2023.2181898⟩
Article dans une revue hal-04022536v1

Honey-induced macrophage stimulation: AP-1 and NF-κB activation and cytokine production are unrelated to LPS content of honey

Anais Raynaud , Lamia Ghezali , Vincent Gloaguen , Bertrand Liagre , Fabien Quero , et al.
International Immunopharmacology, 2013, 17 (3), pp.874-879. ⟨10.1016/j.intimp.2013.09.014⟩
Article dans une revue hal-00935717v1

Ursolic acid induces apoptosis through caspase-3 activation and cell cycle arrest in HaCat cells

Pierre-Olivier Harmand , Raphaël E. Duval , Bertrand Liagre , Chantal Jayat-Vignoles , Jean-Louis Beneytout , et al.
International Journal of Oncology, 2003, ⟨10.3892/ijo.23.1.105⟩
Article dans une revue hal-01651248v1

Berberis libanotica extract targets NF-κB/COX-2, PI3K/Akt and mitochondrial/caspase signalling to induce human erythroleukemia cell apoptosis

Saada Diab , Chloé Fidanzi-Dugas , David Yannick Leger , Lamia Ghezali , Marion Millot , et al.
International Journal of Oncology, 2015, 47 (1), pp.220-230. ⟨10.3892/ijo.2015.3012⟩
Article dans une revue hal-01200642v1
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Shining a Light on Prostate Cancer: Photodynamic Therapy and Combination Approaches

Hicham Wahnou , Ibtissam Youlyouz-Marfak , Bertrand Liagre , Vincent Sol , Mounia Oudghiri , et al.
Pharmaceutics, 2023, 15 (6), pp.1767. ⟨10.3390/pharmaceutics15061767⟩
Article dans une revue hal-04142473v1

Development of a downscale sedimentation field flow fractionation device for biological event monitoring.

Gaëlle Bégaud-Grimaud , Bertrand Liagre , Serge Battu , Jean-Louis Beneytout , Philippe Cardot , et al.
Journal of Chromatography A, 2009, 1216 (52), pp.9125-33. ⟨10.1016/j.chroma.2009.08.042⟩
Article dans une revue istex hal-00595226v1

2′-Hydroxy-4-methylsulfonylchalcone enhances TRAIL-induced apoptosis in prostate cancer cells

Bassel Ismael , Catherine Fagnère , Youness Limami , Lamia Ghezali , Christelle Pouget , et al.
Anti-Cancer Drugs, 2015, 26 (1), pp.74-84. ⟨10.1097/CAD.0000000000000163⟩
Article dans une revue hal-01103009v1

A novel form of melanoma apoptosis resistance: Melanogenesis up-regulation in apoptotic B16-F0 cells delays ursolic acid-triggered cell death

Aline Pinon , Youness Limami , Ludovic Micallef , Jeanne Cook-Moreau , Bertrand Liagre , et al.
Experimental Cell Research, 2011, 317 (12), pp.1669 - 1676. ⟨10.1016/j.yexcr.2011.04.014⟩
Article dans une revue hal-01650370v1

Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells

Cécile Corbière , Bertrand Liagre , Faraj Terro , Jean-Louis Beneytout
Cell Research, 2004, 14 (3), pp.188-196. ⟨10.1038/⟩
Article dans une revue hal-02340685v1

Analysis of the in vitro and in vivo effects of photodynamic therapy on prostate cancer by using new photosensitizers, protoporphyrin IX-polyamine derivatives

Chloé Fidanzi-Dugas , Bertrand Liagre , Guillaume Chemin , Aurélie Perraud , Claire Carrion , et al.
Biochimica et Biophysica Acta (BBA) - General Subjects, 2017, 1861 (7), pp.1676-1690. ⟨10.1016/j.bbagen.2017.02.003⟩
Article dans une revue hal-02421432v1

Structure–function relationship for saponin effects on cell cycle arrest and apoptosis in the human 1547 osteosarcoma cells: a molecular modelling approach of natural molecules structurally close to diosgenin

Patrick Trouillas , Cécile Corbière , Bertrand Liagre , Jean-Luc Duroux , Jean-Louis Beneytout
Bioorganic and Medicinal Chemistry Letters, 2005, 13 (4), pp.1141-1149. ⟨10.1016/j.bmc.2004.11.031⟩
Article dans une revue istex hal-02340679v1

Relationship between cell cycle and diosgenin-induced megakaryocytic differentiation of HEL cells using sedimentation field-flow fractionation

C. Cailleteau , L. Micallef , C. Lepage , Philippe Cardot , Jean-Louis Beneytout , et al.
Analytical and Bioanalytical Chemistry, 2010, 393 (3), pp.1273-1283
Article dans une revue hal-00597570v1

Metformin and Probiotics in the Crosstalk between Colitis-Associated Colorectal Cancer and Diabetes in Mice

Sahar Al Kattar , Rosalyn Jurjus , Aline Pinon , David Yannick Leger , Abdo Jurjus , et al.
Cancers, 2020, 12 (7), pp.1857. ⟨10.3390/cancers12071857⟩
Article dans une revue hal-02922060v1

Design and multi-step synthesis of chalcone-polyamine conjugates as potent antiproliferative agents

Benjamin Rioux , Christelle Pouget , Chloë Fidanzi-Dugas , Aurélie Gamond , Aurélie Laurent , et al.
Bioorganic and Medicinal Chemistry Letters, 2017, 27 (18), pp.4354-4357. ⟨10.1016/j.bmcl.2017.08.024⟩
Article dans une revue hal-02491124v1

Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1547 osteosarcoma cells.

Cécile Corbière , Bertrand Liagre , Arnaud Bianchi , Karim Bordji , Michel Dauça , et al.
International Journal of Oncology, 2003, 22 (4), pp.899-905. ⟨10.3892/ijo.22.4.899⟩
Article dans une revue hal-02340687v1