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Article Dans Une Revue Bioorganic and Medicinal Chemistry Letters Année : 2004

Amino porphyrins as photoinhibitors of Gram-positive and -negative bacteria

Résumé

Twenty four aminoporphyrin derivatives have been tested in vitro for their antibacterial photoactivity against Escherichia coli and Staphylococcus aureus. Two of these compounds, bearing polyamine units, exhibited a significant activity especially against Gram-negative bacteria (E. coli). Twenty four aminoporphyrin derivatives have been tested in vitro for their antibacterial photoactivity against Escherichia coli and Staphylococcus aureus. Two of these compounds, bearing polyamine units (17–18) exhibited a significant activity especially against gram-negative bacteria. For 17, 18: R1=R2=R3=R4=H, a=CH3, b=CHCH2 and c=(CH2)2COspermidine for 17, c=(CH2)2COspermine for 18.

Dates et versions

hal-02895616 , version 1 (09-07-2020)

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Vincent Sol, Pierre Branland, Vincent Chaleix, Robert Granet, Michel Guilloton, et al.. Amino porphyrins as photoinhibitors of Gram-positive and -negative bacteria. Bioorganic and Medicinal Chemistry Letters, 2004, 14 (16), pp.4207-4211. ⟨10.1016/j.bmcl.2004.06.016⟩. ⟨hal-02895616⟩
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