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Article Dans Une Revue Planta Medica Année : 2014

Uncommon Chlorinated Xanthone and Other Antibacterial Compounds from the Lichen Cladonia incrassata

Résumé

Bioassay-guided fractionation of an extract of the lichen Cladonia incrassata against Staphylococcus aureus led to a novel compound, 1,5-dihydroxy-2,4,6-trichloro-7-methylxanthone (1), along with six known compounds: (−)-usnic acid (2), didymic acid (3), condidymic acid (4), squamatic acid (5), thamnolic acid (6), and prasinic acid (7). Didymic, condidymic, and prasinic acids were isolated for the first time from C. incrassata. Didymic, condidymic, and (−)-usnic acids were active against S. aureus (a minimum inhibitory concentration of 7.5 µg/mL).
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Dates et versions

hal-01058414 , version 1 (26-08-2014)

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Amandine Dieu, Marion Millot, Yves Champavier, Lengo Angèle Mambu, Vincent Chaleix, et al.. Uncommon Chlorinated Xanthone and Other Antibacterial Compounds from the Lichen Cladonia incrassata. Planta Medica, 2014, 80, pp.931-935. ⟨10.1055/s-0034-1382827⟩. ⟨hal-01058414⟩
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